mitoNET is a new Canadian Network of researchers, clinicians, patient & advocates, academic institutions, NGO's and industry partners working together towards a common goal: to unveil how mitochondria act as the common thread connecting most chronic diseases and, through that understanding, to transform our ability to prevent, diagnose and treat many common human diseases and revolutionize patient care.
Mitochondria are organelles that drive cellular metabolism—they convert our diet of sugar, fat and protein into about 90% of the chemical energy needed by our cells.
Mitochondrial dysfunction, therefore, impacts organ systems with high-energy demand, such as the brain, muscle, heart, kidney, gastrointestinal tract, and liver.
Researchers now recognize that mitochondrial dysfunction plays a significant role in common, chronic diseases, including neurodevelopmental, neuropsychiatric and neurodegenerative disorders, cardiovascular disease, cancer, and many metabolic disorders.
mitoNET will transform our understanding of the role of mitochondria in human health, including common chronic diseases that range from mood to metabolism.
Within 10 years, clinicians in Canada—and the world—will assess mitochondrial health as part of routine care. mitoNET will deliver the tools and knowledge to realize this vision.