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Leukemia

Steven Chan, PhD

Dr. Chan received his medical and research training at Stanford University in California where he earned his MD and PhD degree in Immunology. He completed his internal medicine residency and adult hematology fellowship at Stanford Hospital and Clinics. He joined Princess Margaret Cancer Centre as a clinician scientist and staff physician in the Leukemia Program in August 2015. His current research is focused on the role of mitochondria in AML development and cell fate decision in leukemia stem cells. In addition, his lab is interested in developing novel AML therapies that target metabolic pathways. See More

Aaron D. Schimmer, MD, PhD, FRCPC

Dr. Schimmer is a Staff Physician and Senior Scientist at the Princess Margaret Cancer Centre, University Health Network and Ontario Cancer Institute.  He is a member of the executive of the Ontario Cancer Institute and Dept of Medical Oncology and Hematology at the Princess Margaret.  Dr. Schimmer holds the Baker Chair in Leukemia and Related Diseases at the University Health Network.  Dr. Schimmer is a Professor in the departments of Medicine and Medical Biophysics at the University of Toronto.  He is also the Past President and executive member of the Canadian Hematology Society.

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The Schimmer lab is focused in on developing new therapeutic strategies for leukemia with an interest in targeting unique mitochondrial and metabolic vulnerabilities in AML and AML stem cells.   He has advanced 3 drugs into clinical trial from his lab and has been the Principal Investigator on 9 additional clinical trials of novel agents for leukemia.  Dr. Schimmer is the author of over 200 publications and is an inventor on over 20 patent applications. He has received over 35 awards and honours for academic achievement including Member of the American Society of Clinical Investigation, Scholar in Clinical Research by the Leukemia and Lymphoma Society, and the Bernard and Francine Dorval young investigator award from the Canadian Cancer Society. See More